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Skin Booster

Rejuran Healer

Polynucleotide, placed where the skin has thinned

Rejuran Healer delivers polynucleotide (PN) — purified DNA fragments extracted from salmon — into the skin to restore the environment the dermis works in. It is not a filler: nothing is being shaped or added as volume.

Treatment time10–20 min
AnaesthesiaTopical cream, or sedation-assisted comfort
DowntimeSame-day return
IntervalEvery 3–4 weeks

※ The final plan and cost are confirmed by your physician after an in-person examination at the clinic. Results and recovery vary by individual.

Rejuran Healer

What PN is, and what it is not

Polynucleotide is a chain of purified DNA fragments obtained from salmon. It is a biocompatible material — the body does not treat it as a foreign object — and it is placed in the skin to improve the conditions inside it rather than to sit under a line and hold it up.

That distinction matters when you are choosing between treatments. A filler occupies space and changes shape on the day. Rejuran works on skin quality: texture, oil-water balance, the resilience of skin that has been thinned by repeated lasers or years of sun. The change is cumulative, which is why it is planned as a short course rather than a single visit.

What it is used for

Three directions, all of them about the condition of the skin rather than its outline.

Oil and water balance
Sebum output settles and the surface texture becomes smoother as the skin holds moisture more evenly.
Firmness
The elastic fibre network that thins with age is supported, so skin feels more resilient rather than fuller.
Skin's own recovery
The skin's regenerative activity is stimulated, which is the point of the treatment for skin weakened by irritation or frequent procedures.

Session by session

Rejuran is planned as a course at 3–4 week intervals. The pattern below is what we describe at consultation; response varies between individuals.

AFTER SESSION 1
Texture feels softer, sebum output settles, and skin tone looks clearer.
AFTER SESSION 2
Firmness improves and fine lines soften; flaking and rough patches reduce.
AFTER SESSION 3
A natural tightening appears, the skin looks better supported, and pores appear smaller.
AFTER SESSION 4
The changes accumulated over the course hold for longer before maintenance is considered.

Rejuran and Rejuran HB

Two formulations, chosen at consultation according to what your skin needs and how sensitive you are to injection.

Rejuran / Rejuran iRejuran HB
CompositionPolynucleotide (PN) onlyPN with hyaluronic acid and lidocaine
What it addsThe full dose is given over to PNHydration from HA, and less discomfort during injection
Usual deliveryNeedle-free Mirajet, or hand injectionHand injection or automated injector
Where it suitsRejuran i is used for thin skin such as around and under the eyesBroader facial areas where hydration is also wanted

Skin this is usually considered for

Firmness lost with age
Skin that has softened rather than dropped, where volume is not the issue.
Photoageing and pigment
Skin marked by sun exposure over years.
Fine lines around eyes and mouth
Areas where the skin is thin and lines have multiplied.
Skin damaged by irritation
Skin left sensitive by chemical exposure or over-treatment.
Dryness and flaking
Skin that dries out quickly and does not hold moisture.
Thinned by repeated lasers
A common reason patients come to us, and one the treatment is well matched to.

How it is delivered, and why that is decided per patient

The material is only half of it. The route it takes into the skin changes both comfort and evenness, so the doctor chooses the route at consultation.

Mirajet — needle-free
The material is delivered as a micro-jet without a needle, so there is no needle pain and no raised bumps to wait out. Nothing is lost in the syringe; the full dose reaches the skin.
I-JECT — automated injection
Digital delivery at a constant speed, which evens out the sensation and the amount placed. Suited to repeat courses such as boosters and collagen injections.
Multi-needle injector
Nine 34G needles place the material at one set depth across a wide area, more evenly than by hand, with depth chosen for the thickness of your skin. Bumps are uniform and typically absorb within about a day.
Hand injection
Still the right choice in some areas, and entirely dependent on the hand doing it. Our physicians have over 20 years of clinical practice, worked to keep discomfort and bruising down.

How Symphony runs it

Product names travel. The structure around them is what differs between clinics.

The doctor plans and performs
The formulation, the depth and the delivery route are decided by the physician who then carries out the treatment — not handed over after the consultation.
Skin measured before planning
Moisture, pores and skin condition are measured with our skin analysis system so the plan starts from readings rather than impressions.
Comfort handled up front
Topical anaesthetic cream as standard, with an inhaled comfort option and a private single room for every treatment.
A plan you take home
Because most overseas patients cannot return every three weeks, the interval, the home care and what to avoid are written out before you fly, and you can reach us afterwards.

Questions we are asked most

Is Rejuran a filler?

No. A filler adds volume and changes shape. Rejuran places polynucleotide in the skin to improve its condition — texture, moisture balance and resilience. If you want a change in contour, that is a different conversation.

Can I fly home the same day?

Yes. The treatment takes 10 to 20 minutes and you can return to normal activity straight away. With needle delivery, small raised bumps are normal and usually absorb within about a day; with Mirajet there are none to wait out.

How many sessions will I need?

Rejuran is normally planned as a course at 3–4 week intervals, with the number decided at consultation. If your stay in Korea is short, we plan around the dates you actually have and discuss what can be done on a later visit.

Does it hurt?

Sensation depends on the delivery route as much as the material. Mirajet is needle-free; the automated injector keeps the speed constant; Rejuran HB contains lidocaine. Topical anaesthetic cream is applied as standard and an inhaled comfort option is available.

Can it be combined with other treatments?

Frequently, yes. Rejuran is one of the materials we combine within a Symphony Custom Booster session, and it is often planned alongside lifting treatments. What is combined, and in what order, is decided at consultation.

What we look at before anything is switched on

01
Skin analysis first
Skin type, thickness and condition are assessed before settings are chosen, so energy levels and tips match the skin in front of us rather than a default protocol.
02
Planned and performed by a physician
The doctor who consults you draws up the plan and carries it out. Nothing is delegated after the consultation.
03
Layered, not single-device
Treatments are combined by depth and symptom, with intervals planned around your recovery.
04
Care that continues
Conditioning before, calming immediately after, and home-care guidance through recovery — then the next session is adjusted to how your skin responded.
BEFORE & AFTER

Records from our own treatment rooms

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MIRAJET + Rejuran + Exosome
MIRAJET + Rejuran + Exosome
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