Exosome
Cell-to-cell signals, dosed to the area being treated
Exosomes are the signalling particles cells release to communicate with each other. Delivered into skin that has been damaged or inflamed, they support cell vitality, prompt regeneration and help the skin barrier recover.
※ The final plan and cost are confirmed by your physician after an in-person examination at the clinic. Results and recovery vary by individual.
What an exosome actually is
An exosome is not a drug and not a filler. It is a vesicle that a cell secretes to send instructions to other cells — and one derived from stem cells carries the signals those cells would send. Placed in the skin, it works on the environment: cell activity, the balance of the skin's microflora, the barrier that keeps irritation out.
Exosomes are not interchangeable. Source material, purity and concentration differ between products, and so does what each is best suited to. Which one is used, and how much of it, is decided at consultation rather than fixed by a menu.
How it works on the skin
- 01The signal is deliveredStem cell conditioned media is placed into the skin, carrying the messages cells use to coordinate repair.
- 02Cell activity risesSkin cells become more active and regeneration is induced in tissue that has been damaged or inflamed.
- 03The barrier recoversThe skin's defensive barrier is restored and strengthened, which is why calming and resilience are the usual reasons for choosing it.
Two-dimensional and three-dimensional culture
How the stem cells were cultured before the exosomes were harvested changes what you are receiving. The exosome we use is produced by three-dimensional culture, made under Anterogen's patented technology.
| Conventional 2D culture | 3D culture | |
|---|---|---|
| Growing environment | Cells grow flat on a surface | A three-dimensional environment resembling body tissue |
| Cell behaviour | Cells may not grow properly and cell-specific function can drop | Cell activity close to that inside the body |
| PGE2 (immune modulator) | Lower secretion | Secreted at higher concentration |
| Consequence | — | Suppression of immune response and of inflammatory cytokine secretion |
| Suited to | — | Sensitive, reactive and breakout-prone skin |
The exosome we use
The range we work with
Four exosomes are kept in the clinic. Which is used is a consultation decision, based on skin condition and what you are treating.
What it is usually chosen for
How Symphony runs it
The vial is the same wherever you buy it. What differs is who decides the dose and who holds the handpiece.
Questions we are asked most
Is exosome treatment suitable for sensitive skin?
It is one of the reasons patients are offered it. Exosomes obtained through three-dimensional culture secrete the immune modulator PGE2 at higher concentration, which is associated with suppression of inflammatory cytokine secretion. Suitability is still confirmed at consultation.
What is the difference between the exosomes on offer?
Source material, purity, concentration and the growth factors present differ, and so does what each suits. Limelight is cord blood-derived at over 99.5% purity; Neostem HGF contains hepatocyte growth factor. We explain which we are proposing and why before treatment.
Can I fly home the same day?
Yes. Treatment takes 10 to 20 minutes and you return to normal activity straight away. With needle delivery, small bumps are normal and usually absorb within about a day; with needle-free Mirajet there are none.
How many sessions are needed?
Sessions are usually spaced 3 to 4 weeks apart, with the number decided at consultation. If your time in Korea is short, we plan around the dates you have and set out what is best left to a later visit.
Can it be combined with other boosters?
Yes — exosome is one of the materials we combine within a Symphony Custom Booster session. What it is paired with depends on what your skin is short of, and is decided at consultation.
※ Exosome treatment supports the condition of the skin; it does not add volume or reshape the face. Results, sensation and recovery vary by individual, and no outcome is guaranteed. Suitability, the product used and the treatment plan are confirmed by your physician at consultation.
What we look at before anything is switched on
You have read this far. Start with one photo.
Free, one-on-one, and nothing is decided until you see the plan in person.
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